Molecular Assembly Lines in Active Droplets

CSBD director Frank Jülicher publishes study in the journal of Physical Review Letters on the theory of self-organization of molecular assembly lines in active droplets

A fundamental question in biology is how complexes of several molecules can assemble reliably. Tyler Harmon and Frank Jülicher of the Max Planck Institute for the Physics of Complex Systems have now shown that a molecular assembly line can be self-organized by active droplets where it can form spontaneously. This assembly line arranges different assembly steps spatially so that a specific order of assembly is achieved and incorrect assembly is suppressed. They have shown how assembly bands are positioned and controlled and discuss the rate and fidelity of assembly as compared to other assembly scenarios. 

T. S. Harmon and F. Jülicher, Phys. Rev. Lett. 128, 108102 (2022)